货号: | 589104 | 规格: | 25 µg |
品牌: | 热销产品 | 价格: | ¥ |
产品分类: | 特价奥特莱斯专区 | 研究领域: | |
CAS编号: | 分子量: | ||
分子式: | 别名: | T-cell growth factor (TCGF), Eosinophil differentiation factor (EDF), Killer cell helper factor (KHF), Macrophage-activating factor for cytotoxicity I (MAF-C I), Thymocyte differentiation factor (TDF) | |
储存条件: | Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to six months, or at -70°C or colder until the expiration date. | 运输条件: | |
货期: | 应用: | ||
说明书: | 备注: | ||
产品描述 | |||
香港精准12码库存现货,特价销售Recombinant Human IL-2 (carrier-free)! | 产品信息 品名:Recombinant Human IL-2 (carrier-free) 别名:T-cell growth factor (TCGF), Eosinophil differentiation factor (EDF), Killer cell helper factor (KHF), Macrophage-activating factor for cytotoxicity I (MAF-C I), Thymocyte differentiation factor (TDF) 品牌:Biolegend 货号:589104 规格:25 µg | 产品描述 IL-2 was discovered through its function as a T cell growth factor (TCGF), and plays a pivotal role in immune responses against pathogenic infection. Recognition and binding of the foreign Ags by the TCRs stimulate both the secretion of IL-2 and the expression of IL-2Rs on the T cell surface. Subsequently, the IL-2/IL-2R interaction activates the intracellular Ras/Raf/MAPK, JAK/STAT, and PI3K/AKT signal pathways, and ultimately stimulates the growth, differentiation, and survival of the Ag-selected cytotoxic T cells. Human IL-2 acts on murine and human T cells, and its receptors are shared by others cytokines. IL-2Rα is an IL-2–specific receptor, IL-2Rβ is shared with IL-15 and the γ chain that is a common receptor shared by many cytokines including IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. | 产品细节 1)Source Human IL-2, amino acids Ala21-Thr153 (Accession # NM_000586), was expressed in insect cells. 2)Molecular Mass The 133 amino acid recombinant protein (Ala21-Thr153) has a predicted molecular mass of 15418 Da. The DTT-reduced and the non-reduced protein migrate at approximately 15 kD by SDS-PAGE. The N-terminal amino acid is Ala. 3)Purity Purity is >95%, as determined by Coomassie stained SDS-PAGE. 4)Formulation The protein was 0.22 µm filtered protein solution is in 0.1% TFA, 30% acetonitrile. 5)Storage & Handling: Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to six months, or at -70°C or colder until the expiration date. For maximum results, quick spin vial prior to opening. The protein can be aliquoted and stored at -20°C or colder. Stock solutions can also be prepared at 50 - 100 µg/mL in appropriate sterile buffer, carrier protein such as 0.2 - 1% BSA or HSA can be added when preparing the stock solution. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles. |