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产品名称 Recombinant Human IL-6/IL-6R alpha Protein Chimera 25ug(R&D Systems 8954-SR 现货特卖)
货号: 8954-SR 规格: 25ug
品牌: 热销产品 价格:
产品分类: 特价奥特莱斯专区 研究领域:
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香港精准12码库存现货,特价销售Recombinant Human GM-CSF Protein 25ug

| 产品信息

品名:Recombinant Human IL-6/IL-6R alpha Protein Chimera

品牌:R&D Systems

货号:8954-SR

规格:25 ug


产品属性

Alternate NamesIL-6/IL-6R alpha Complex
Purity>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Level<0.10 EU per 1 μg of the protein by the LAL method.
ActivityMeasured by its ability to inhibit M1 mouse myeloid leukemia cell proliferation. The ED50 for this effect is 2.5-12.5 ng/mL.
Accession #P08887 (IL-6 R alpha) & P05231 (IL-6)
N-terminal Sequence AnalysisLeu20 (Human IL-6R alpha)
Predicted Molecular Mass59 kDa
SDS-PAGE78-93 kDa, reducing conditions


产品描述

Interleukin-6 (IL-6) is a pleiotropic, alpha -helical, 22-28 kDa phosphorylated and variably glycosylated cytokine that plays important roles in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression (1-5). Mature human IL-6 is 183 amino acids (aa) in length and shares 39% aa sequence identity with mouse and rat IL-6 .  IL-6 can also function as an anti-inflammatory molecule, as in skeletal muscle where it is secreted in response to exercise . In addition, it enhances hematopoietic stem cell prolife.








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